Space has become an increasingly attractive destination for research, manufacturing and more, as its microgravity environment offers a unique platform for scientific exploration. Microgravity causes changes in biological systems and alters fundamental physical phenomena, enabling novel experiments. Since 2011, the Center for the Advancement of Science in Space has selected more than 200 research projects, ranging from developing new drug therapies to monitoring tropical cyclones, and launched them to the ISS National Lab where ground-breaking discoveries are being made using this unique orbiting research facility.