The International Space Station National Laboratory is a crewed low Earth orbit (LEO) platform for research, development, and education that inspires innovation and provides opportunities for discovery to benefit humankind.
Conducting research on the ISS National Laboratory demonstrates to U.S. citizens and the world that space is accessible, affordable, and capable of supporting the research and development necessary to make the fundamental business case for sustainable industrial demand in LEO. The ISS National Laboratory has a congressionally mandated mission to maximize use of this unique space-based facility to accelerate knowledge and foster commercial development through research and development.
NLRA 2023-10: Igniting Innovation: Science in Space to Cure Disease on Earth
Open period: 8/8/2023 – 3/8/2024
The purpose of this NLRA is to solicit proposals focused on flight research on the ISS to address the goals of the Cancer MoonshotSM initiative and accelerate the translation of stem cell and organoid-based disease models and advanced technologies for biomanufacturing.

Technology in Space Prize 2023 (funded by Boeing and CASIS in partnership with MassChallenge)
Open period: 7/12/2023 – 10/30/2023
The prize is open to startups that participate in a MassChallenge program and provides an opportunity to utilize the ISS National Lab to conduct innovative research and technology development (R&D).

NLRA 2023-8: Technology Advancement and Applied Research Leveraging the ISS National Lab
Open period: 5/15/2023 – 10/9/2023
The purpose of this NLRA is to solicit proposals focused on flight investigations within applied R&D, translational medicine, technology readiness level maturation, and technology demonstration.

2024 – 2025 ISS National Lab Solicitation Schedule
NLRA 2024-1: In-Space Production Applications: Tissue Engineering and Biomanufacturing
RELEASE: October 2023
CONCEPT SUMMARY SUBMISSION PERIOD: September – November 2024
FULL PROPOSALS DUE: February 2024
PROJECT SELECTION: April 2024
NLRA: Leveraging the ISS for Education and Workforce Development
RELEASE: January 2024
CONCEPT SUMMARY SUBMISSION PERIOD: January – March 2024
FULL PROPOSALS DUE: May 2024
PROJECT SELECTION: July 2024
NLRA: Technology Advancement and Applied Research Leveraging the ISS National Lab
RELEASE: January 2024
CONCEPT SUMMARY SUBMISSION PERIOD: January – April 2024
FULL PROPOSALS DUE: June 2024
PROJECT SELECTION: September 2024
NLRA: In-Space Production Applications: Advanced Manufacturing and Materials
RELEASE: February 2024
CONCEPT SUMMARY SUBMISSION PERIOD: February – April 2024
FULL PROPOSALS DUE: June 2024
PROJECT SELECTION: August 2024
NLRA: Technology Advancement and Applied Research Leveraging the ISS National Lab
RELEASE: May 2024
CONCEPT SUMMARY SUBMISSION PERIOD: May – June 2024
FULL PROPOSALS DUE: October 2024
PROJECT SELECTION: December 2024
Technology in Space Prize (funded by Boeing and CASIS in partnership with MassChallenge)
RELEASE: July 2024
CONCEPT SUMMARY SUBMISSION PERIOD: July – August 2024
FULL PROPOSALS DUE: October 2024
PROJECT SELECTION: December 2024
Please note that the ISS National Lab will not consider proposals received from a non-U.S. person, as defined in the Code of Federal Regulations (CFR).