The International Space Station National Laboratory is a crewed low Earth orbit (LEO) platform for research, development, and education that inspires innovation and provides opportunities for discovery to benefit humankind.
Conducting research on the ISS National Laboratory demonstrates to U.S. citizens and the world that space is accessible, affordable, and capable of supporting the research and development necessary to make the fundamental business case for sustainable industrial demand in LEO. The ISS National Laboratory has a congressionally mandated mission to maximize use of this unique space-based facility to accelerate knowledge and foster commercial development through research and development.
Tissue Chips in Space 2.0
Release Date: 7/25/2024
The purpose of this Notice of Funding Opportunity (NOFP) is to develop multi-organ automated microphysiological systems (MPS) to study the effects of microgravity on the human body in low Earth orbit on the International Space Station National Lab.
NLRA 2024-9: Igniting Innovation: Science in Space to Cure Disease on Earth
Open period: 8/15/2024 – 3/3/2025
The purpose of this NLRA is to solicit proposals focused on flight projects to address challenges that hinder progress in preventing, diagnosing, and treating some of the most challenging diseases of our time.
Technology in Space Prize 2024 (Funded by Boeing and CASIS in Partnership with MassChallenge)
Open period: 7/10/2024 – 10/28/2024
The prize is open to startups that participate in a MassChallenge program and provides an opportunity to utilize the ISS National Lab to conduct innovative research and technology development (R&D).
NLRA 2024-7: Technology Advancement and Applied Research Leveraging the ISS National Lab
Open period: 5/14/2024 – 10/16/2024
The purpose of this NLRA is to solicit proposals focused on flight investigations within applied R&D, translational medicine, technology readiness level maturation, and technology demonstration.
2024 – 2025 ISS National Lab Solicitation Schedule
NLRA: Follow-on Projects
RELEASE: October 2024
CONCEPT SUMMARY SUBMISSION PERIOD: Continuous
FULL PROPOSALS SUBMISSION PERIOD: Continuous
PROJECT SELECTION: Continuous
NLRA for Applied Research, Translational Science and Tech Dev 2025: Cycle 1
RELEASE: January 2025
CONCEPT SUMMARY SUBMISSION PERIOD: January – March
FULL PROPOSALS SUBMISSION PERIOD: May
PROJECT SELECTION: July
NLRA: Leveraging the ISS for Education and Workforce Development
RELEASE: February 2025
CONCEPT SUMMARY SUBMISSION PERIOD: February – April
FULL PROPOSALS SUBMISSION PERIOD: June
PROJECT SELECTION: September
NLRA: In-Space Production Applications
RELEASE: March 2025
CONCEPT SUMMARY SUBMISSION PERIOD: March – April
FULL PROPOSALS SUBMISSION PERIOD: July
PROJECT SELECTION: September
NLRA for Applied Research, Translational Science and Tech Dev 2025: Cycle 2
RELEASE: May 2025
CONCEPT SUMMARY SUBMISSION PERIOD: May – August
FULL PROPOSALS SUBMISSION PERIOD: October
PROJECT SELECTION: December
Technology in Space Prize (funded by Boeing and CASIS in partnership with MassChallenge)
RELEASE: July 2025
CONCEPT SUMMARY SUBMISSION PERIOD: July – August
FULL PROPOSALS SUBMISSION PERIOD: October
PROJECT SELECTION: December
Igniting Innovation 2025
RELEASE: August 2025
CONCEPT SUMMARY SUBMISSION PERIOD: September
ROADMAPS SUBMISSION PERIOD: November
FULL PROPOSALS SUBMISSION PERIOD: March 2026
PROJECT SELECTION: May 2026
Please note that the ISS National Lab will not consider proposals received from a non-U.S. person, as defined in the Code of Federal Regulations (CFR).
