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The International Sp

The International Space Station National Laboratory, in partnership with global investment partners Context Ventures, Cook Inlet Region, Inc., Draper Associates, Draper University, E2MC, and Stellar Ventures, announces the eight early-stage startups selected for the two tracks of the 2026 Orbital Edge Accelerator program.

Sentinel Track (focused on space technologies and dual-use applications):
- Aspect Aerospace is developing a Single-Board Satellite (SBS), a mass-producible satellite designed for on-demand, large-scale deployment in very low Earth orbit (VLEO). A host spacecraft can deploy up to 100 single-board satellites, forming rapid-response swarms to support PNT (positioning, navigation, and timing), remote sensing, bistatic radar, and distributed sensing systems with hundred-kilometer-scale apertures.
- Mithril Space is building electrostatically actuated reflectors, which are large, lightweight antennas that reshape in orbit with no moving parts. This technology enables adaptive, multi-orbit radar for space domain awareness at a much lower mass than phased arrays and at a fraction of the cost of existing reflectors.
- Polaris Semiconductor’s BK30 Enhanced Linear Regulators use a proprietary photonic design to deliver ultra-clean, efficient, and compact DC power for space applications, including RF (radio frequency) systems, communications, sensors, and high-speed data systems, where electrical noise and size, weight, and power (SWaP) are critical constraints.
- Vaxon Space is developing satellites that operate in VLEO. The satellites are designed with air-breathing propulsion technology that will allow them to capture higher-resolution imagery, deliver faster communications, and provide persistent monitoring for defense and commercial applications without the need for conventional fuel.

Disrupt Track (focused on in-space manufacturing and space bio opportunities):
- Astrileux produces Extreme Ultraviolet (EUV) photomasks, the precision templates needed to manufacture the next generation of AI-powered computer chips, enabling smarter devices and faster computing.
- Aura Life Science will adapt its cyanobacteria photosynthetic biomanufacturing platform, which converts light and CO₂ into high-value proteins and enzymes, for use in the space environment.
- Micro-gRx harnesses microgravity to biomanufacture high-purity, scalable cell-free nanomedicines, unlocking regenerative therapies for heart disease.
- Tensr builds autonomous factories that manufacture robots and use AI to continuously learn through self-improvement.

Read the full press release: ow.ly/emon50Zz4mT
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The International Space Station (ISS) National Laboratory

Solving some of the world’s most pressing challenges through space-based research.

Where? In space.
Low Earth orbit (LEO), approximately 250 miles above the Earth.

Research in Space Benefits Humanity

Upward Volume 9, Issue 2
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EXPLORE RESULTS FROM RESEARCH CONDUCTED IN SPACE

Upward Volume 9, Issue 2 Available Now

In this issue’s cover story, discover how brain organoids on the ISS are helping researchers study aging, neurodegeneration, and disease-relevant changes linked to Alzheimer’s, Parkinson’s, and Rett syndrome. Other features discuss how unexpected findings from Sanofi’s space research could help improve vaccines and how a new holographic microscope could one day help scientists find life on distant worlds.

Photo documentation of the Materials ISS Experiment Flight Facility (MISSE-FF) platform aboard the International Space Station.

looking for a research opportunity?

National Lab research announcements (NLRAs) seek proposals that advance R&D in key areas with demonstrated potential to develop into sustainable markets and benefit humanity.

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