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iss065e242370 (Aug. 14, 2021) European Space Agency astronaut and Expedition 65 Flight Engineer Thomas Pesquet works on the Cardinal Muscle investigation in the Life Sciences Glovebox aboard the International Space Station. This study tests whether such engineered tissues cultured in space could provide a model for studying muscle loss and assessing possible therapeutics prior to clinical trials. Date Created: 2021 08 14

Media Credit: Image courtesy of NASA

NLRA 2023-2: In-Space Production Applications: Tissue Engineering and Biomanufacturing

NLRA open period: 10/3/2022 – 2/28/2023

The purpose of this ISS National Lab Research Announcement (NLRA) is to solicit proposals for applied research and development seeking to demonstrate space-based biomanufacturing activities in microgravity. Flight projects selected via this research announcement may be awarded funding to enable support for development and mission integration and operations for projects that will be implemented on the ISS.

CASIS, in coordination with NASA, has identified multiple ISS National Lab lines of business that support strategic priorities and programmatic focus areas aimed at bringing value to our nation and enabling a robust and scalable market in low Earth orbit. For the in-space production line of business, research concepts are desired for which space-based testing can uniquely enable technical solutions to known science and engineering challenges and the creation of new products and business opportunities.  The objective is to use the unique ISS environment to develop, test or mature products and processes that have a demonstrated potential to produce near-term, positive direct or indirect economic impact.

This research announcement will follow a two-step proposal submission process. Before being invited to submit a full proposal, all interested investigators must first complete and submit for review a Step 1: Concept Summary.

FREQUENTLY ASKED QUESTIONS
Click here to view frequently asked questions regarding NLRA 2023-2 

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  • Step 1.1: Download NLRA 2023-2 and Required Step 1 Forms

    • The deadline for submissions has passed

    Download Step 1 Forms

  • Step 1.2: Concept Summary Submission

    Upload your Step 1: Concept Summary by pressing the “Click to Submit” button below. Please convert your document to a PDF prior to uploading.

    Click to Submit

  • Step 2.1: Download Step 2 Required Forms (Invitation Only)

    CASIS will notify all offerors of the review results of their Step 1: Concept Summary.

    Download Step 2 Required Forms

    Full proposal development periods for Invited Step 2: Full Proposals

    • Update: Step 2: Full Proposal Due Date: March 14, 2023

  • Step 2.2: Full Proposal Submission

    If you were invited to submit a Step 2: Full Proposal, upload your submission by pressing the “Click to Submit” button below. Please convert your document to a PDF prior to uploading.

    Upload Step 2 Submission

Thank you for your interest in conducting research on the ISS National Lab! For questions regarding this research announcement, please contact [email protected] and reference NLRA2022-3 in the subject line.

** Please verify that none of the information submitted is subject to the export control laws of the United States, such as the EAR or the ITAR; if any information is subject to such laws, please mark all pages containing such information and identify the appropriate export control jurisdiction and classification. **

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