METRICS

CASIS has compiled a series of dashboard metrics that encompasses all of the major functions for the organization. The charts on this page are dedicated to showcasing all progress that has been made within these core functions, from the International Space Station U.S. National Laboratory utilization to grant value and outreach.

Projects
Funding / Grants
Stem
Awareness
ISS Utilization

Projects Awarded to Customers

YTD FY2018

31

14	ISS National Lab Return Customers
17	ISS National Lab New Customers

Total Value of CASIS Grants Awarded

YTD FY2018

$4,647,372

Cumulative from Year to Year

Solicitations / Competitions

YTD FY2018

5 Project Proposals Generated

YTD FY2018

124 Total Peer Reviewed Results Published in Scientific Journals

Total 2005-2018

119

*Some citations included in this metric were published prior to the designation in 2005 by the US Congress creating the ISS National Lab, but were included because the publications describe ISS flight hardware and/or flight data for investigations sponsored by the ISS National Lab and flown to the ISS.

Grants Funding and Mission Based Costs Paid

Q3 FY2018

$261,128	Academic
$1,115,761	Commercial
$50,000	Other Govt Agency
$142,160	Mission Based Costs
$1,569,049	Total

TOTALS FY2012 $2,120,000

TOTALS FY2013 $6,146,511

TOTALS FY2014 $6,028,157

TOTALS FY2015 $5,648,088

TOTALS FY2016$6,818,907

TOTALS FY2017$7,243,341

Q1 FY2018$1,177,849

Q2 FY2018$1,189,445

Allocation of Expenses

Q3 FY2018

53.8%	Direct
12.8%	Indirect
33.6%	Grants

FY2012

FY2013

FY2014

FY2015

FY2016

FY2017

Q1 FY2018

Q2 FY2018

YTD FY2018

$11,650,000

STEM Programs (active)

YTD FY2018

23 Number of Participants Engaged in STEM Activities*

YTD FY2018

785,460

*students, educators and other participants

Outreach Events

Conferences and Industry Sponsored Events

YTD FY2018

8 Speaking Opportunities

YTD FY2018

38

Total Media Impact

Website Visitors

YTD FY2018

79,084

Twitter Followers

YTD FY2018

123,166

cumulative

News Mentions

YTD FY2018

5,620

Social Media Engagement

YTD FY2018

143,071

Facebook, Twitter, and Instagram

ISS National Lab Payloads Manifested

YTD FY2018

38 ISS National Lab Payloads Delivered

YTD FY2018

25 In-orbit commercial facilities

YTD FY2018

12 In-orbit commercial facility managers

YTD FY2018

7 Maximize Utilization: CASIS to use 50% of U.S. allocation onboard the ISS.

Increment	Upmass (kg)	Downmass (kg)	Crewtime (hrs)
Increment	Actuals	Actuals	Allocation*	Actuals^	Reserve	Usage**
Inc 37/38 (Sep 2013-Mar 2014)	334.7	7.9	427	78.42	-	18%
Inc 39/40 (Mar 2014-Sep 2014)	389.1	197.8	386	70.75	-	18%
Inc 41/42 (Sep 2014-Mar 2015)	716	705.5	346	130.29	-	38%
Inc 43/44 (Mar 2015-Sep 2015)*	538.3	165.93	229	223.33	-	98%
Inc 45/46 (Sept 2015-Mar 2016)	384.6	0	293	125.75	-	43%
Inc 47/48 (Mar 2016-Sept 2016)	760.9	313.54	356	314.25	-	88%
Inc 49/50 (Sept 2016-Mar 2017)	392	83	403²	311.58	-	77%
Inc 51/52 (Mar 2017-Sept 2017)	931	300	328	446.58	-	136%
Inc 53/54 (Sept 2017-Mar 2018)	1580	358	503	349	165	54%

Data through 4/13/2017

* “Allocation” is defined as the baselined number of crew time hours allocated by NASA at increment minus 3 months to the ISS National Lab for prioritized utilization to directly support in-orbit ISS NL payload utilization operations.
^ “Actuals” are defined as the definite and verified number of crew time hours that were utilized to support in-orbit ISS NL payload utilization operations. This data is collected reported and verified by NASA after the actual in-orbit operations have been completed.
** ”Usage” is defined as the percentage of ISS National Lab allocated crew time hours that were actually utilized during a given increment pair.

Notes:
1. Incudes SpaceX CRS-7 upmass/downmass
2. Inc 49/50 I-3 crew time allocation was 312 hours. Additional crew time allocation was added over the course of the increment pair.

	Actual FY12	Actual FY13	Actual FY14	Actual FY15	Actual FY16	Actual FY17	Q1 FY2018	Q2 FY2018	Q3 FY2018	YTD FY2018
Solicitations / Competitions	2	5	5	7	7	4	3	1	1	5

	Actual FY14	Actual FY15	Actual FY16	Q1 FY2017	Q2 FY2017	Q3 FY2017	Q4 FY2017	Final FY2017
CASIS seed funding toward total project cost	17%	19%	35%	29%	24%	10%	38%	26¹%

	Actual FY12	Actual FY13	Actual FY14	Actual FY15	Actual FY16	Actual FY1Y	Q1 FY2018	Q2 FY2018	Q3 FY2018	YTD FY2018
Total Value of CASIS Grants Awarded	$2,051,079	$4,103,288	$5,634,911	$4,143,829	$5,331,133	$6,078,192	$1,085,639	$1,898,015	$1,663,718	$4,647,372

Publication	Period	Total
Aunins TR, Erickson KE, Prasad N, Levy SE, Jones A, Shrestha S, Mastracchio R, Stodieck L, Klaus D, Zea L and Chatterjee A (2018) Spaceflight Modifies Escherichia coli Gene Expression in Response to Antibiotic Exposure and Reveals Role of Oxidative Stress Response. Front. Microbiol. 9:310. doi: 10.3389/fmicb.2018.00310	Q2 FY18	7 YTD FY2018
Malley KR, Koroleva O, Miller I, Sanishvili R, Jenkins CM, Gross RW, Korolev S. The structure of iPLA(2)? reveals dimeric active sites and suggests mechanisms of regulation and localization. Nat Commun. 2018 Feb 22;9(1):765. doi: 10.1038/s41467-018-03193-0. PubMed PMID: 29472584; PubMed Central PMCID: PMC5823874.	Q2 FY18
Baio J, Martinez AF, Bailey L, Hasaniya N, Pecaut MJ, Kearns-Jonker M. Spaceflight Activates Protein Kinase C Alpha Signaling and Modifies the Developmental Stage of Human Neonatal Cardiovascular Progenitor Cells. Stem Cells Dev. 2018 Feb 12. doi: 10.1089/scd.2017.0263. [Epub ahead of print] PubMed PMID: 29320953.	Q2 FY18
Childress P, Brinker A, Gong CS, Harris J, Olivos DJ 3rd, Rytlewski JD, Scofield DC, Choi SY, Shirazi-Fard Y, McKinley TO, Chu TG, Conley CL, Chakraborty N, Hammamieh R, Kacena MA. Forces associated with launch into space do not impact bone fracture healing. Life Sci Space Res (Amst). 2018 Feb;16:52-62. doi: 10.1016/j.lssr.2017.11.002. Epub 2017 Nov 11. PubMed PMID: 29475520; PubMed Central PMCID: PMC5828031.	Q2 FY18
Hatzistergos KE, Jiang Z, Valasaki K, Takeuchi LM, Balkan W, Atluri P, Saur D, Seidler B, Tsinoremas N, DiFede D, Hare JM. Simulated microgravity impairs cardiac autonomic neurogenesis from neural crest cells. Stem Cells Dev. 2018 Jan 16. doi: 10.1089/scd.2017.0265. [Epub ahead of print] PubMed PMID: 29336212.	Q2 FY18
Boguraev, A.-S., Christensen, H. C., Bonneau, A. R., Pezza, J. A., Nichols, N. M., Giraldez, A. J., ? Alvarez Saavedra, E. (2017). Successful amplification of DNA aboard the International Space Station. NPJ Microgravity, 3, 26. http://doi.org/10.1038/s41526-017-0033-9	Q1 FY18
Dajnowicz S, Johnston RC, Parks JM, Blakeley MP, Keen DA, Weiss KL, Gerlits O, Kovalevsky A, Mueser TC. Direct visualization of critical hydrogen atoms in a pyridoxal 5'-phosphate enzyme. Nat Commun. 2017 Oct 16;8(1):955. doi: 10.1038/s41467-017-01060-y. PubMed PMID: 29038582; PubMed Central PMCID: PMC5643538.	Q1 FY18
Jha R, Singh M, Wu Q, Gentillon C, Preininger MK, Xu C (2017). Downregulation of LGR5 Expression Inhibits Cardiomyocyte Differentiation and Potentiates Endothelial Differentiation from Human Pluripotent Stem Cells. Stem Cell Reports 9(2): 513-527.	Q4 FY17	13 YTD FY2017
Zea L, Larsen M, Estante F, Qvortrup K, Moeller R, Dias de Oliveira S, Stodieck L, Klaus D (2017). Phenotypic Changes Exhibited by E. coli Cultured in Space. Front Microbiol. 8: 1598.	Q4 FY17
Parra M, Jung J, Boone TD, Tran L, Blaber EA, Brown M, et al (2017). Microgravity validation of a novel system for RNA isolation and multiplex quantitative real time PCR analysis of gene expression on the International Space Station. PLoS One. 12(9): e0183480.	Q4 FY17
Huemmrich KF, Entcheva Campbell PK, Gao BC, Flanagan LB, Goulden M (2017). ISS as a Platform for Optical Remote Sensing of Ecosystem Carbon Fluxes: A Case Study Using HICO. IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing 10(10): 1-16.	Q4 FY17
Dajnowicz S, Parks JM, Hu X, Gesler K, Kovalevsky AY, Mueser TC (2017). Direct Evidence That an Extended Hydrogen Bonding Network Influences Activation of Pyridoxal 5′-Phosphate in Aspartate Aminotransferase. J Biol Chem. 292(14):5970-5980.	Q3 FY17
Morokuma J, Durant FR, Williams KB, Finkelstein JM, Blackiston DJ, Clements T, Reed DW, Roberts M, Jain M, Kimel K, Trauger SA, Wolfe BE, Levin M (2017). Planarian regeneration in space: Persistent anatomical, behavioral, and bacteriological changes induced by space travel. Regeneration 4:85-102.	Q3 FY17
Desai PK, Tseng H, Souza GR (2017). Assembly of Hepatocyte Spheroids Using Magnetic 3D Cell Culture for CYP450 Inhibition/Induction. Int J Mol Sci 18(5):e1085.	Q3 FY17
Paul AL, Sng NJ, Zupanska AK, Krishnamurthy A, Schultz ER, Ferl RJ (2017). Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight? PLoS ONE 12(6): e0180186.	Q3 FY17
Souza GR, Tseng H, Gage JA, Mani A, Desai P, Leonard F, Liao A, Longo M, Refuerzo JS, Godin B. (2017) Magnetically Bioprinted Human Myometrial 3D Cell Rings as A Model for Uterine Contractility. Int J Mol Sci 23;18(4):e683.	Q2 FY17
Owens GE, New DM, Olvera AI, Manzella JA, Macon BL, Dunn JC, Cooper DA, Rouleau RL, Connor DS, Bjorkman PJ. Acta Crystallogr F Struct Biol Commun. 2016 Oct 1;72(Pt 10):762-771.	Q1 FY17
Bruno G, Canavese G, Liu X, Filgueira CS, Sacco A, Demarchi D, Ferrari M, Grattoni A. Nanoscale. 2016 Nov 10;8(44):18718-18725.	Q1 FY17
Banco MT, Mishra V, Ostermann A, Schrader TE, Evans GB, Kovalevsky A, Ronning DR (2016). Ronning Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states. PNAS 113(48):13756-13761.	Q1 FY17
Zea L, Prasad N, Levy SE, Stodieck L, Jones A, Shrestha S, et al. (2016) A Molecular Genetic Basis Explaining Altered Bacterial Behavior in Space. PLoS ONE 11(11): e0164359.	Q1 FY17
Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin Z, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C (2016). A Human Pluripotent Stem Cell Model of Catecholaminergic Polymoprhic Ventricular Tachyardia Recapitulates Patient-Specific Drug Responses. Disease Models and Mechanism 9(9):927-939.	Q4 FY16	10 total FY2016
Jha R, Wu Q, Singh M, Preininger MK, Han P, Ding G, Cho HC, Jo H, Maher KO, Wagner MB, Xu C (2016). Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells. Scientific Reports 6: 30956.	Q4 FY16
Fleet T, Stashi E, Zhu Bokai, Rajapakshe K, Marcelo KL, Kettner NM, Gorman BK, Coarfa C, Fu L, O'Malley B, York B (2016). Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology. Journal of Biological Rhythm (5):443-460.	Q4 FY16
Zeng X, Han I, Abd-El-Barr M, Anderson JE, Chi JH, Zafonte RD, Teng YD (2016). The Effects of Thermal Precondition on Oncogenic and Intraspinal Cord Growth Features of Human Glioma Cells. Cell Transplantation.	Q4 FY16
Shi J, Lee S, Uyeda M, Tanjaya J, Kim JK, Pan HC, Reese P, Stodieck L, Lin A, TingK, Kwak JH, Soo C (2016) Guidelines for Dual Energy X-ray Absorptiometry Analysis of Trabecular Bone-rich Regions in Mice: Improved Precision, Accuracy, and Sensitivity for Assessing Longitudinal Bone Changes. Tissue Engineering Part C: Methods, 22 (5).	Q3 FY16
Ferl, R.J., and Paul, A.L. (2016) The effect of spaceflight on the gravity-sensing auxin gradient of roots: GFP reporter gene microscopy on orbit. NPJ Microgravity 2:15023.	Q2 FY16
Amin, R., Penta, B., & deRada, S. (2015). Occurence and Spatial Extent of HABs on West Florida Shelf 2002-Present. IEEE Geoscience and Remote Sensing, 12(10): 2080-2084.	Q1 FY16
Amin, R., Lewis, M.D., Lawson, A., Gould Jr., R.W., Martinolich, P., Li, R.R., Ladner, S., & Gallegos, S. (2015) Comparative Analysis of GOCI Ocean Color Products. Sensors, 15: 25703-25715.	Q1 FY16
Zhu, B., Gates, L., Stashi, E., Dasgupta, S., Gonzales, N., Dean, A., et al. (2015). Coactivator-dependent oscillation of chromatin accessibility circadian gene amplitude via rev-erb loading. Molecular Cell, 60(5), 769-783.	Q1 FY16
Jha, R., Xu, R-H., Xu, C. (2015) Efficient Differentiation of Cardiomyocytes from Human Pluripotent Stem Cells with Growth Factors. Methods Mol Biol 1299:115-31.	Q1 FY16
Ng, J.D., Baird, J.K., Coates, L., Garcia-Ruiz, J.M., Hodge, T.A., & Huang, S. (2015). Large-volume protein crystal growth for neutron macromolecular crystallography. Acta Crystallographica Section F Structural Biology Communications, 71(4): 358-370.	FY15	11 total FY15
Martinez EM, Yoshida MC, Candelario TLT, Hughes-Fulford M (2015). Spaceflight and simulated microgravity cause a significant reduction of key gene expression in early T-cell activation. American Journal of Physiology Regulatory, Integrative and Comparative Physiology 308(6):R480-R488.	FY15
Amin, R., & Shulman, I. (2015). Hourly turbidity monitoring using Geostationary Ocean Color Imager fluorescence bands. Journal of Applied Remote Sensing,096024-096024.	FY15
Bruno, G., Geninatti, T., Hood, R. L., Fine, D., Scorrano, G., Schmulen, J., Hosali, S., Ferrari, M., Grattoni, A. (2015). Leveraging electrokinetics for the active control of dendritic fullerene-1 release across a nanochannel membrane. Nanoscale, 7(12), 5240-5248.	FY15
Fuentes, T.I., Appleby, N., Raya, M., Bailey, L., Hasaniya, N., Stodieck, L., et al. (2015) Simulated Microgravity Exerts an Age-Dependent Effect on the Differentiation of Cardiovascular Progenitors Isolated from the Human Heart. PLoS ONE 10(7): e0132378.	FY15
Owens, G., New, D., West, A., & Bjorkman, P. (n.d.). (2015) Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1. Journal of Molecular Biology, 427(15): 2507-2519.	FY15
Hughes-Fulford, M., Chang, T., Martinez, E., & Li, C. (2015). Spaceflight alters expression of microRNA during T-cell activation. The FASEB Journal, 15(277392).	FY15
Tseng, H., Gage, J.A., Shen, T., Haisler, W.L., Neeley, S.K., Shiao, S., et al. (2015). A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging. Scientific Reports, 5(13987).	FY15
Pollonini, L., Padhye, N. S., Re, R., Torricelli, A., Simpson, R. J., & Dacso, C. C. (2015). Pulse transit time measured by photoplethysmography improves the accuracy of heart rate as a surrogate measure of cardiac output, stroke volume and oxygen uptake in response to graded exercise. Physiological Measurement, 36(5), 911-924.	FY15
Fleet, T., Zhang, Bin., Lin,F., Zhu B., Dasgupta, S., Stashi, et al. (2015). SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis. PNAS, 112(44).	FY15
Countryman, S., Stumpe, M., Crow, S., Adler, F., Greene, M., Vonshak, M., & Gordon, D. (2015). Collective search by ants in microgravity. Frontiers in Ecology and Evolution Front. 3(25).	FY15
Li Y, Xu C, Ma T. (2014) In vitro organogenesis from pluripotent stem cells. Organogenesis 10, 159-163.	FY14	3 total FY14
Nguyen DC, Hookway TA, Wu Q, Jha R, Preininger MK, Chen X, et al. (2014) Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells. Stem Cell Reports 3, 260-268.	FY14
Stashi, E., Lanz, R., Mao, J., Michailidis, G., Zhu, B., Kettner, N., et al. (2014). SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm. Cell Reports, 6(4), 633-645.	FY14

	Actual FY12	Actual FY13	Actual FY14	Actual FY15	Q1 FY2016	Q2 FY2016	Q3 FY2016	Q4 FY2016	Total FY2016
Products or services created	0	0	0	1	0	1			1

	Actual FY14	Actual FY15	Actual 2016	Actual 2017	Q1 FY2018	Q2 FY2018	YTD FY2018
In-orbit commercial facilities	4	5	7	12	12	12	12
In-orbit commercial facility managers	3	4	5	7	7	7	7

	Actual FY12	Actual FY13	Actual FY14	Actual FY15	Actual FY16	Actual FY17	Q1 FY2018	Q2 FY2018	Total FY2018
Academic	$420,000	$2,157,857	$2,655,310	$1,632,428	$1,883,415	$1,858,756	$236,603	$247,214	$483,817
Commercial	$1,700,000	$2,410,593	$2,179,083	$3,175,665	$4,577,405	$4,671,674	$763,120	$707,360	$1,470,480
Other Government Agency**	$0	$350,000	$200,799	$521,870	$0	$0	$0	$35,000	$35,000
Mission Based Costs	$0	$1,228,061	$992,965	$318,125	$358,087	$712,884	$178,126	$203,871	$381,997
Total	$2,120,000	$6,146,511	$6,028,157	$5,648,088	$6,818,907	$7,243,341	$1,177,849	$1,193,445	$$2,371,294

	Actual FY12	Actual FY13	Actual FY14	Actual FY15	Actual FY16	Actual FY17	Q1 FY2018	Q2 FY2018	YTD FY2018
News mentions (clips, blogs)	NA	599	3,891	3,734	3,223	6,213	4,142	1,478	5,620
Twitter followers^	1,529	36,061	54,273	78,362	94,500	114,696	117,833	123,166	123,166
Website visitors	13,541	66,809	74,653	122,962	121,099	182,717	27,077	52,007	79,084
Social media engagement (Facebook, Twitter, and Instagram)	NA	NA	NA	89,802	295,402	1,021,883	40,386	102,685	143,071

METRICS

Projects Awarded to Customers

YTD FY2018

31

14

17

Total Value of CASIS Grants Awarded

YTD FY2018

$4,647,372

Cumulative from Year to Year

Solicitations / Competitions

YTD FY2018

5

Project Proposals Generated

YTD FY2018

124

Projects Awarded

Total FY2016

22

Total Peer Reviewed Results Published in Scientific Journals

Total 2005-2018

119

Products or Services Created

Total FY2016

1

Grants Funding and Mission Based Costs Paid

Q3 FY2018

TOTALS FY2012 $2,120,000

TOTALS FY2013 $6,146,511

TOTALS FY2014 $6,028,157

TOTALS FY2015 $5,648,088

TOTALS FY2016$6,818,907

TOTALS FY2017$7,243,341

Q1 FY2018$1,177,849

Q2 FY2018$1,189,445

Allocation of Expenses

Q3 FY2018

FY2012

FY2013

FY2014

FY2015

FY2016

FY2017

Q1 FY2018

Q2 FY2018

Sponsored Program/External Funding for Grants

YTD FY2018

$11,650,000

STEM Programs (active)

YTD FY2018

23

Number of Participants Engaged in STEM Activities*

YTD FY2018

785,460

Outreach Events

Conferences and Industry Sponsored Events

YTD FY2018

8

Speaking Opportunities

YTD FY2018

38

Subject Matter Workshops

Total FY2016

3

Total Media Impact

Thought Leadership Publications*

Total FY2016

1

Website Visitors

YTD FY2018

79,084

Twitter Followers

YTD FY2018

123,166

News Mentions

YTD FY2018

5,620

Social Media Engagement

YTD FY2018

143,071