In 2015 a workshop was held to outline the basic science requirements for a long-term protein crystallization program onboard the International Space Station National Lab including accessibility/timing, resources (flight/ground), education and funding. The workshop was focused on an ISS National Laboratory MMCG initiative for repetitive, low-cost crystallization in microgravity providing a platform for human healthcare discovery to users across the discipline including commercial, other government agencies, academia and private research. In addition, inspiring the next generation through experiential learning opportunities will be a key component.
The 2018 workshop will (1) discuss progress made toward the goals outlined in the 2015 workshop, (2) identify steps necessary to accomplish remaining goals, (3) present new opportunities uncovered, (4) and formulate future goals for the program.
Location
Hauptman-Woodward Medical Research Institute
700 Ellicott St., Buffalo, New York 14203
Date
July 19th 2018.
This is just before the start of the annual ACA meeting that will be in Toronto Canada starting the 20th.
Attend
If you would like to participate in the 2018 workshop please contact Marc Giulianotti at mgiulianotti@issnationallab.org
Agenda
- 8:00 AM
Check in and Light Breakfast
- 8:30 AM
Welcome
Speaker - the ISS National Lab - 8:45 AM - 10:15 AM
Session 1: Lessons Learned From Microgravity Crystallization
8:45
Top Ten Considerations When Sending Your Proteins to Crystallize in Space
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Joe Ng, Ph.D.
iXpressGenes Inc., Hudson Alpha Institute for Biotechnology9:00
Past, Present and Planned the ISS National Lab PCG Payloads
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April Spinale
the ISS National Lab9:15
Room Termperature X-ray and Neutron Crystallography of Human Acetylcholinesterase to Inform the Design of Accelerated Reactivators
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Andrey Kovalesky, Ph.D.
Research and Development Scientist at the Neutron Scattering Division Oak Ridge National Laboratory9:30
Surprises in Space
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Edward Snell, Ph.D.
President and CEO of Hauptman-Woodward Medical Research Institute9:45
Questions and Answers
the ISS National Lab Moderated - 10:15
Break
- 10:30 AM - 12:00 PM
Session 2: Lessons Learned From Microgravity Crystallization
10:30
A COTS Approach to Microgravity PCG
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Kristofer Gonzalez-DeWhitt
Former contractor (ATL) at Eli Lilly & Company, Consultant for The Bionetics Corporation10:40
Diffusion Cells, Membranes and Dynamic Control
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Paul Todd, Ph.D.
Chief Scientist Emeritus, Consultant at Techshot, Inc.10:50
UAB Implementation Partnership Capabilities
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Robyn Rouleau
Assoc. Director, UAB/EITD11:00 AM
Payload, Operation & Science Services including Vapor-Diffusion and Counter-Diffusion Cell Capabilities (PCAM and enhanced DCAM)
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Dan Carter, Ph.D.
CEO/Chief Scientist. New Century Pharmaceuticals, Inc.11:10 AM
Microscopes on the ISS: Present and Future Possibilities.
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William Meyer, Ph.D.
USRA NASA Project Scientist for the Advanced Colloids Experiment (ACE)
11:20 AM
Session Questions and Answers
the ISS National Lab Moderated - 12:00 PM
Box Lunch Served
- 12:15 - 1:30 PM
Session 3: Solicitations and Other Applications
12:15
Real Time PCG
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Craig Kundrot, Ph.D.
Director, Space Life and Physical Sciences Research & Applications Division, NASA12:30
Utilizations RFP
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the ISS National Lab12:45
Microfluidics for In Situ Crystallography
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Sarah Perry, Ph.D.
Assistant Professor Department of Chemical Engineering, University of Massachusetts Amherst1:00
Inorganic Salt Crystallizations by Middle and High School Students
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Ilia Guzei, Ph.D.
Director of Crystallography at University of Wisconsin–Madison1:15
Session Questions and Answers
the ISS National Lab Moderated - 1:45 PM
Break Out Session
- 3:00
Networking and Tours